Publications

SELECTED PUBLICATIONS

1. Diggle, S. P., Griffin, A. S., Campbell, G. S. & West, S. A. (2007) Cooperation and conflict in quorum sensing bacterial populations. Nature. 450: 411-414.

2. Rumbaugh, K. P., Diggle, S. P., Watters, C., Ross-Gillespie, A., Griffin, A. S. & West, S. A. (2009) Quorum sensing and the social evolution of bacterial virulence. Current Biology. 19: 341-345.

3. Wilder, C. N., Diggle, S. P. & Schuster, M. (2011) The roles of las, rhl, and pqs quorum-sensing systems in cooperation and cheating in Pseudomonas aeruginosa. ISME J. 5: 1332-1343.

4. Diggle, S. P. (2010) Microbial communication and virulence: lessons from evolutionary theory. Microbiology. 156: 3503-3512.

5. West, S. A., Griffin, A. S., Gardner, A. & Diggle, S. P. (2006) Social evolution theory for microorganisms. Nature Reviews Microbiology. 4: 597-607.

FULL LIST OF PUBLICATIONS (Journal articles and book chapters)

51. Popat, R., Pollitt, E. J. G., Brown, S. P., Williams, P., West, S. A. & Diggle, S. P. (2012) An experimental test of signalling theory in bacteria. In preparation.
 
50. Popat, R., Crusz, S. A., Messina, M., Williams, P., West, S. A. & Diggle, S. P. (2012) Quorum sensing and the tragedy of the commons in bacterial biofilms. Submitted.

49. Rumbaugh, K. P., Trivedi, U., Watters, C., Burton-Chellew, M., Diggle, S. P. & West, S. A. (2012) Kin selection, quorum sensing and virulence in pathogenic bacteria. Submitted.

48. Darch, S. E., West, S. A., Winzer, K. & Diggle, S. P. (2012) Density-dependent fitness benefits in quorum sensing bacterial populations. Submitted.

47. Diggle, S. P. & Williams, P. (2012) Quorum sensing. In Brenners Encyclopedia of Genetics (Ed. Maloy & Hughes). In press.

46. Goldstone, R. J., Popat, R., Fletcher, M. P., Crusz, S. A. & Diggle, S. P. (2012) Quorum sensing and social interactions in microbial biofilms. In Microbial Biofilms: Current research, methods and applications (Ed. Lear & Lewis). Caister Academic Press.

45. Stacey, A. R., Diggle, S. P. & Whiteley, M. (2011) Rules of engagement: defining bacterial communication. Current Opinion in Microbiology. In press.

44. Johansson, E. M. V., Kadam, R. U., Rispoli, G., Crusz, S. A., Bartels, K., Diggle, S. P., Cámara, M., Williams, P., Jaeger, K. E., Darbre, T. & Reymond, J. L. (2011) Inhibition of Pseudomonas aeruginosa biofilms with a glycopeptide dendrimer containing D-amino acids. Medicinal Chemistry Communications. 5: 418-420.

43. Wilder, C. N., Diggle, S. P. & Schuster, M. (2011) The roles of las, rhl, and pqs quorum-sensing systems in cooperation and cheating in Pseudomonas aeruginosa. ISME J. 5: 1332-1343.

42. Liu, X., Jia, J., Popat, R., Ortori, C. A., Li, J., Diggle, S. P., Gao, K. & Cámara, M. (2011) Characterisation of two quorum sensing systems in the endophytic Serratia plymuthica strain G3: differential control of motility and biofilm formation according to life-style. BMC Microbiology. 11: 26.

41. Heeb, S., Fletcher, M. P., Chhabra, S. R., Diggle, S. P., Williams, P. & Camara, M. (2011) Quinolones: from antibiotics to autoinducers. FEMS Microbiology Reviews. 35: 247-274.

40. Diggle, S. P., Fletcher, M. P., Camara, M. & Williams, P. (2011) Detection of 2-alkyl-4-quinolones using biosensors. Methods in Molecular Biology. 692: 21-30.

39. Diggle, S. P. & Popat, R. (2010) Social interactions in a unicellular world. Microbiology Today. November issue. 220-223.

38. Diggle, S. P. (2010) Microbial communication and virulence: lessons from evolutionary theory. Microbiology. 156: 3503-3512.

37. Diggle, S. P. (2010) Book review on "The Scourging Angel: The Black Death in the British Isles" by Benedict Gummer. Microbiology Today. May issue.

36. Fletcher, M. P., Heeb, S., Chhabra, S. R., Diggle, S. P., Williams, P. & Camara, M. (2010) 2-alkyl-4-quinolone signalling in Pseudomonas aeruginosa. In Pseudomonas. (ed. Alain Filloux & Juan Ramos). pp. 29-57. Springer Netherlands.

35. Jiricny, N., Diggle, S. P., West, S. A., Evans, B. A., Ballatyne, G., Ross-Gillespie, A. & Griffin, A. S. (2010) Fitness correlates with the extent of cheating in a bacterium. Journal of Evolutionary Biology. 23: 738-747.

34. Brown, S. P., West, S. A., Diggle, S. P. & Griffin, A. S., (2009) Social evolution in microorganisms and a Trojan horse approach to medical intervention strategies. Philosophical Transactions of the Royal Society B. 364: 3157-3168.

33. Zaborin, A., Romanowski, K., Gerdes, S., Holbrook, C., Lepine, F., Long, J., Poroyko, V., Diggle, S. P., Wilke, A., Rhigetti, K., Morozova, I., Babrowski, T., Liu, D. C., Zaborina, O. & Alverdy, J. C. (2009) Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1. Proceedings of the National Academy of Sciences USA. 106: 6327-6332.

32. Skindersoe, M. E., Zeuthen, L. H., Brix, S., Fink, L. N., Lazenby, J., Whittall, C., Williams, P., Diggle, S. P., Froekiaer, H., Cooley, M. & Givskov, M. (2009) Pseudomonas aeruginosa quorum sensing signal molecules interfere with dendritic cell induced T cell proliferation. FEMS Immunology and Medical Microbiology. 55: 335-345.

31. Rumbaugh, K. P., Diggle, S. P., Watters, C., Ross-Gillespie, A., Griffin, A. S. & West, S. A. (2009) Quorum sensing and the social evolution of bacterial virulence. Current Biology. 19: 341-345.

30. Johansson, E., Crusz, S. A., Kolomiets, E., Buts, L., Kadam, R. U., Cacciarini, M., Bartels, K. M., Diggle, S. P., Camara, M., Williams, P., Loris, R., Nativi, C., Rosenau, F., Jaeger, K. E., Dabre, T. & Reymond, J. L. (2008) Inhibition and dispersion of Pseudomonas aeruginosa biofilms by glycopeptide dendrimers targeting the fucose-specific lectin LecB. Chemistry and Biology. 15: 1249-1257.

29. Popat, R., Crusz, S. A. & Diggle, S. P. (2008) The social behaviours of bacterial pathogens. British Medical Bulletin. 87: 63-75.

28. Dubern, J. F. & Diggle, S. P. (2008) Quorum sensing signalling by 2-alkyl-4-quinolones in Pseudomonas aeruginosa and other bacterial species. Molecular Biosystems. 4: 882-888.

27. von Bodman, S. B., Willey, J. M. & Diggle, S. P. (2008) Cell-to-cell communication in bacteria: United we stand. Journal of Bacteriology. 190: 4377-4391. Meeting review of the 2007 3rd cell-to-cell conference in bacteria (Austin Texas).

26. Diggle, S. P., West, S. A., Gardner, A. & Griffin, A. S. (2008) Communication in bacteria. In Sociobiology of Communication: an interdisciplinary perspective (ed. David Hughes & Patrizia D'Ettorre). Oxford University Press. pp. 11-31.

25. Diggle, S. P., Heeb, S., Dubern, J. F., Fletcher, M. P., Crusz, S. A., Williams, P. & Camara, M. (2008) Quorum sensing in Pseudomonads. In Pseudomonas: Model organism, pathogen, cell factory (ed. B. Rehm). Wiley-VCH. pp. 167-194.

24. Romero, M., Diggle, S. P., Heeb, S., Camara, M. & Otero, A. (2008) Quorum quenching activity in Anabaena sp. PCC 7120: identification of AiiC, a novel AHL-acylase. FEMS Microbiology Letters. 280: 73-80.

23. Diggle, S. P., Griffin, A. S., Campbell, G. S. & West, S. A. (2007) Cooperation and conflict in quorum sensing bacterial populations. Nature. 450: 411-414.

22. Diggle, S. P., Crusz, S. A. & Camara, M. (2007) Quorum sensing. Current Biology. 17: R907-R910.

21. Holden, M.T.G., Diggle, S. P. & Williams, P. (2007) Quorum sensing. In Encyclopedia of Life Sciences. Wiley-VCH.

20. Fletcher, M. P., Diggle, S. P., Crusz, S. A., Chhabra, S. R., Camara, M. & Williams, P. (2007) A dual biosensor for 2-alkyl-4-quinolone quorum sensing signal molecules. Environmental Microbiology. 9: 2683-2693.

19. West, S. A., Diggle, S. P., Buckling, A., Gardner, A. & Griffin, A. S. (2007) The social lives of microbes. Annual Review of Ecology, Evolution and Systematics. 38: 53-77.

18. Fletcher, M. P., Diggle, S. P., Camara, M. & Williams, P. (2007) Biosensor-based assays for PQS, HHQ and related 2-alkyl-4-quinolone quorum sensing signal molecules. Nature Protocols. 2: 1254-1262.

17. Diggle, S. P., Gardner, A., West, S. A. & Griffin, A. S. (2007) Evolutionary theory of bacterial quorum sensing: When is a signal not a signal? Philosophical Transactions of the Royal Society B. 362: 1241-1249.

16. Diggle, S. P., Matthijs, S., Wright, V. J., Fletcher, M. P., Chhabra, S. R., Lamont, I. L., Kong, X., Hider, R. C., Cornelis, P., Camara, M. & Williams, P. (2007) The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multi-functional roles in quorum sensing and iron entrapment. Chemistry & Biology. 14: 87-96.

15. Lumjiaktase, P., Diggle, S. P., Loprasert, S., Tungpradabkul, S., Daykin, M., Camara, M., Williams, P. & Kunakorn, M. (2006) Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei. Microbiology. 152: 3651-3659.

14. Diggle, S. P., Lumjiaktase, P., Dipilato, F., Winzer, K., Kunakorn, M., Barrett, D., Chhabra, S. R., Camara, M. & Williams, P. (2006) Functional genetic analysis reveals a 2-alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria. Chemistry & Biology. 13: 701-710.

13. West, S. A., Griffin, A. S., Gardner, A. & Diggle, S. P. (2006) Social evolution theory for microorganisms. Nature Reviews Microbiology. 4: 597-607.

12. Diggle, S. P., Stacey, R. E., Dodd, C., Camara, M., Williams, P. & Winzer. K. (2006) The galactophilic lectin, LecA, contributes to biofilm development in Pseudomonas aeruginosa. Environmental Microbiology. 8: 1095-1104.

11. Sio, C. F., Otten, L. G., Cool, R. H., Diggle, S. P., Braun, P. G., Bos, R., Daykin, M., Williams, P. & Quax, W. (2006) Quorum quenching by an N-acyl homoserine lactone acylase of Pseudomonas aeruginosa PAO1. Infection & Immunity. 74: 1673-1682.

10. Diggle, S. P., Cornelis, P., Williams, P. & Camara, M. (2006) 4-Quinolone signalling in Pseudomonas aeruginosa: Old molecules, new perspectives. International Journal of Medical Microbiology. 296: 83-91.

9. Krasnogor, N., Gheorghe, M., Terrazas, G., Diggle, S., Williams, P. & Camara, M. (2005) An appealing computational mechanism drawn from bacterial quorum sensing. Bulletin of the European Association for Theoretical Computer Science. 85: 135-148.

8. Aendekerk, S., Diggle, S. P., Song, Z., Hoiby, N., Cornelis, P., Camara, M. and Williams, P. (2005) The MexGHI-OpmD multidrug efflux pump controls fitness, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication. Microbiology. 151: 1113-1125.

7. Terrazas, G., Krasnogor, N., Georghe, M., Bernardini, F., Diggle, S. & Camara, M. (2005) An environment aware P-system model of quorum sensing. In: New Computational Paradigms. Book series: Lecture Notes in Computer Science. 3526: 479-485. Springer Berlin / Heidelberg.

6. Westfall, L. W., Luna, A. M., Francisco, M. S., Diggle, S. P., Worrall, K. E., Williams, P., Camara, M. and Hamood, A. N. (2004) The Pseudomonas aeruginosa global regulator MvaT specifically binds to the ptxS upstream region and enhances ptxS expression. Microbiology. 150: 3797-3806.

5. Vallet, I., Diggle, S. P., Stacey, R. E., Camara, M., Ventre, I., Lory, S., Lazdunski, A., Williams, P. & Filloux, A. (2004) Biofilm formation in Pseudomonas aeruginosa: Fimbrial cup gene clusters are controlled by the transcriptional regulator MvaT. Journal of Bacteriology. 186: 2880-2890.

4. Diggle, S. P., Winzer, K., Chhabra, S. R., Worrall, K. E., Camara, M. & Williams, P. (2003) The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Molecular Microbiology. 50: 29-43.

3. Pritchard, D., Hooi, D., Watson, E., Chow, S., Telford, G., Bycroft, B., Chhabra, S. R., Harty, C., Camara, M., Diggle, S., & Williams, P. (2003) Bacterial quorum sensing signalling molecules as immune modulators. In: Bacterial evasion of host immune responses (ed. B. Henderson & P. Oyston): pp. 201-221. Cambridge University Press.

2. Diggle, S. P., Winzer, K., Lazdunski, A., Williams, P. & Camara, M. (2002) Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-acylhomoserine lactone production and virulence gene expression. Journal of Bacteriology. 184: 2576-2586.

1. Winzer, K., Falconer, C., Garber, N. C., Diggle, S. P., Camara, M. & Williams, P. (2000) The Pseudomonas aeruginosa lectins PA-IL and PA-IIL are controlled by quorum sensing and by RpoS. Journal of Bacteriology. 182: 6401-6411.